Synjectos® is to be used in all bone defects stabilized by an appropriate surgical procedure at the fracture site, e.g. humeral head fractures, distal radius fractures, tibia head impression fractures, calcaneal fractures, filling of benign bone cysts or filling of bony defects after bone harvesting for autologous bone graft and filling of bone cavities of collapsed VB fractures such as wedge fractures (A1.1 and A1.2, A3.1 after additional surgical stabilization) after fracture reduction procedures.