Synjectos® is a synthetic, sterile osteoconductive material for filling of bone defects. The material consists of a powder source consisting of calcium and phosphate salts and a liquid component, consisting of an aqueous phosphate solution. After combining the powder and the liquid by thorough mixing a paste is formed which is hardening into an apatitic structure resembling the inorganic structure of natural bone. No materials of biological origin are used during the manufacturing of Synjectos®
The reabsorption of Synjectos material and the formation of new bone. (see below picture)
Synjectos® is to be used in all bone defects stabilized by an appropriate surgical procedure at the fracture site, e.g. humeral head fractures, distal radius fractures, tibia head impression fractures, calcaneal fractures, filling of benign bone cysts or filling of bony defects after bone harvesting for autologous bone graft and filling of bone cavities of collapsed VB fractures such as wedge fractures (A1.1 and A1.2, A3.1 after additional surgical stabilization) after fracture reduction procedures.
Synjectos® should be used exclusively by surgeons who are familiar with the handling of calcium phosphate cements and the corresponding surgical techniques like treatment of osseous defects.
Radiograph showing recurrent giant cell tumor of the right proximal femur (case 28). (A) The patient was referred to Mie University Hospital (Tsu, Japan) following recurrence of giant cell tumor at proximal part of femur with pathological fracture. (B) Calcium phosphate cement and calcium hydroxyapatite ceramic were implanted and compression hip screw was inserted after curettage. Additional surgery was needed due to local recurrence. (C) At the time of review, limb length discrepancy was 1.5 cm, although the patient can work without any disability as a nurse.
Radiograph showing giant cell tumor of the left distal femur. (A) The patient was referred to Mie University Hospital (Tsu, Japan) following pathological fracture. (B) The tumor was located in the distal region of the femur and adjacent to distal femoral physis. (C) Calcium phosphate cement and calcium hydroxyapatite ceramic were implanted into the bone defect following curettage of the bone tumor.